Janine l. kwapis - Janine L. Kwapis, Yasaman Alaghband, Alberto J. López, Jeffrey M. Long, Xiang Li, Guanhua Shu, Kasuni K. Bodinayake, Dina P. Matheos, Peter R. Rapp, Marcelo A. Wood

 
Aug 30, 2013 · CaMKII and Protein Kinase A (PKA) are thought to be critical for synaptic plasticity and memory formation through their regulation of protein synthesis. Consistent with this, numerous studies have reported that CaMKII, PKA and protein synthesis are critical for long-term memory formation. Recently, … . Stihl fc91 parts diagram

Janine L. Kwapis Present address: Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA, 16802, USA ...The orphan nuclear receptor nurr1, a member of the hormone receptor superfamily for which a ligand has not yet been identified, is encoded by an immediate early gene that can be rapidly induced by different stimuli (Law et al. 1992; Scearce et al. 1993; Davis and Lau 1994; Mages et al. 1994; Murphy and Conneely 1997).This transcription factor is expressed predominantly in the brain (Law et al ...Numerous studies have indicated that maintaining a fear memory after retrieval requires de novo protein synthesis. However, no study to date has examined how the temporal dynamics of repeated retrieval events affect this protein synthesis requirement.Anxiety disorders are thought to reflect deficits in the regulation of fear expression. Evidence from rodent studies implicates the ventromedial prefrontal cortex (vmPFC) in the regulation of conditioned fear.Author links open overlay panel Janine L. Kwapis, Marcelo A. Wood. Show more. Add to Mendeley. Share. ... DA031989) to M.A. Wood, and National Institute on Aging (NIA) T32 grant AG000096-31 to J.L.K. Glossary. Consolidation the process of converting temporary short-term memory (lasting only a few hours) ...Janine Kwapis Page 2 • First Place Award for Oral Presentation, UCI ReMIND Emerging Scientists Symposium, UC Irvine 2015 • NIH T32 Institutional Training Grant Recipient, UCI MIND 2014-2016 • NIH F31 Predoctoral Ruth L. Kirschstein National Research Service Award (NRSA) - 3 year fellowship 2011-2013Sep 22, 2011 · All animals were handled for several days prior to surgery. Rats that underwent surgery were implanted with bilateral cannulas aimed at the amygdala [anteroposterior [AP], −2.8; Lateral [L], +/− 5.0; Ventral [V], −7.2]. Coordinates were chosen based on a rat brain atlas . Before surgery, each rat was anesthetized with an intraperitoneal ... Janine L. Kwapis Y. Alaghband +7 authors M. Wood. Biology, Psychology. Neuropsychopharmacology. 2019; TLDR. It is demonstrated that hippocampal memory updating is impaired with aging and established that the OUL paradigm is an effective, sensitive method of assessing memory updating in rodents. Expand. 19. Highly …Stored memories enter a temporary state of vulnerability following retrieval known as 'reconsolidation', a process that can allow memories to be modified to incorporate new information.Kwapis JL, Alaghband Y, Kramar EA, Lopez AJ, Vogel Ciernia A, White AO, Shu G, Rhee D, Michael CM, Montellier E, Liu Y, Magnan CN, Chen S, Sassone-Corsi P, Baldi P, Matheos DP, Wood MA, 2018. Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory .Janine Kwapis. Janine Kwapis. Janine Kwapis. Madison Clement. Madison Clement ... Robert L. Isaacson. Laszlo Lenard. Robert L. Isaacson. Michael L. Woodruff.memory must be properly retrieved. Long-term memory is typically tested 24h or longer after acquisition, after the consolidation process is complete, and can be very long lasting,Yasaman Alaghband 1 , Janine L Kwapis 2 , Alberto J López 1 , André O White 1 , Osasumwen V Aimiuwu 1 , Amni Al-Kachak 1 , Kasuni K Bodinayake 1 , Nicole C Oparaugo 1 , Richard Dang 2 , Mariam Astarabadi 1 , Dina P Matheos 3 , Marcelo A Wood 4Neurobiology of learning and memory 128, 103-109. , 2016. 114. 2016. Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or amygdala, but not the medial prefrontal cortex. MR Gilmartin, JL Kwapis, FJ Helmstetter. Neurobiology of learning and memory 97 (4), 452-464.Janine L. Kwapis, Timothy J. Jarome, Marieke R. Gilmartin, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 34 Scopus citations. Overview; Fingerprint; Abstract. Protein kinase Mzeta has been the subject of much recent interest, as it is the only molecule currently identified to maintain memory ...jlk855 Janine Kwapis Biography Education B.A., Psychology, Alma College M.S., Behavioral Neuroscience, University of Wisconsin-Milwaukee Ph.D., Behavioral …Added Creator Janine L. Kwapis November 15, 2021 13:11 by Researcher Metadata Database. Published November 15, 2021 13:11 by Researcher Metadata Database. Updated February 28, 2022 22:44 ...Janine L. Kwapis, Timothy J. Jarome, Jonathan L. Lee, Marieke R. Gilmartin, Fred J. Helmstetter. Biology; Research output: Contribution to journal › Article › peer-review. 42 Scopus citations. Overview; Fingerprint; Abstract. Extinction learning underlies the treatment for a variety of anxiety disorders. Most of what is known about the ...Janine L. Kwapis, Ph.D., Department of Biology, Penn State University ... it is unknown whether these biological processes share a common mechanism that is altered with age. Dr. Kwapis will present evidence that epigenetic regulation of the circadian gene Period1 (Per1) in the dorsal hippocampus is critical for memory formation and contributes ...Abstract. Activation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association.The NR2B subunit confers unique properties to the NMDAR and may differentially regulate these two fear memories.Anxiety disorders are thought to reflect deficits in the regulation of fear expression. Evidence from rodent studies implicates the ventromedial prefrontal cortex (vmPFC) in the regulation of conditioned fear.Brain derived neurotropic factor (BDNF) supports neuronal survival, growth, and differentiation and is involved in forms of hippocampus-dependent and independent learning, as well as hippocampus-dependent learning. Extinction learning comprises active inhibition of no-longer relevant learned information, in conjunction with a decreased …Janine L Kwapis, 1, 2 Yasaman Alaghband, 1 Alberto J López, 1 André O White, 3 Rianne R Campbell, 1 Richard T Dang, 1 Diane Rhee, 1 Ashley V Tran, 1 Allison E Carl, 1 Dina P Matheos, 1 and Marcelo A Wood 1, 2, *Finally, Bellfy and Kwapis review the evidence that the reconsolidation process may allow existing memories to update in response to new, relevant information . In their review, the authors outline the major behavioral paradigms used to study reconsolidation and describe the different molecular mechanisms across the brain that …Janine L. Kwapis, PhD THE PAUL BERG EARLY CAREER PROFESSOR IN THE BIOLOGICAL SCIENCES; Assistant Professor of Biology. [email protected]. My research focuses on understanding the epigenetic and molecular basis of long-term memory. I'm particularly interested in understanding how these mechanisms are altered in the aging brain and how epigenetic ...Janine L. Kwapis, Marcelo A. Wood. Biology; Research output: Contribution to journal › Review article › peer-review. 68 Citations (SciVal) Overview; Fingerprint; Abstract. Post-traumatic stress disorder (PTSD) and other anxiety disorders stemming from dysregulated fear memory are problematic and costly. Understanding the molecular ...Janine L. Kwapis: Conceptualization, Writing - original draft, Writing - review & editing, Supervision, Funding acquisition. Declaration of Competing Interest. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.AU - Kwapis, Janine L. AU - Trask, Sydney. AU - Pullins, Shane E. AU - Helmstetter, Fred J. N1 - Funding Information: This work was supported by National Institute of Health (NIH) grants MH112141 and AG053854 (FJH) and startup funds from the College of Agricultural and Life Sciences and the College of Science at Virginia Tech (TJJ).Access the most recent version at doi:10.1101/lm.030510.113 Learn. Mem. 2013 20: 290-294 Marieke R. Gilmartin, Janine L. Kwapis and Fred J. Helmstetter contextual ...Research The Kwapis Lab studies the molecular and epigenetic mechanisms that underlie long-term memory formation, storage, and updating. We want to understand the mechanisms that underlie memory and identify how these mechanisms are dysregulated during aging, leading to age-related memory impairments.Arnau Hervera 1 2 , Francesco De Virgiliis 1 3 4 , Ilaria Palmisano 1 , Luming Zhou 3 , Elena Tantardini 1 , Guiping Kong 3 , Thomas Hutson 1 , Matt C Danzi 5 , Rotem Ben-Tov Perry 6 , Celio X C Santos 7 , Alexander N Kapustin 7 , Roland A Fleck 8 , José Antonio Del Río 2 9 10 , Thomas Carroll 11 , Vance Lemmon 5 , John L Bixby 5 , Ajay M ...Context memory formation is a complex process that requires transcription in many subregions of the brain including the dorsal hippocampus and retrosplenial cortex. One critical gene necessary for memory formation is the circadian gene Period1 (Per1), which has been shown to function in the dorsal hippocampus to modulate spatial memory in addition to its well-documented role in regulating the ...AU - Kwapis, Janine L. N1 - Funding Information: Funding: This research was funded by NIH grants K99/R00AG056586 (J.L.K.) and R21AG068444 (J.L.K.), Whitehall Foundation Grant #2020-05-06 (J.L.K.), startup funds from the Eberly College of Science and Department of Biology at Pennsylvania State University (J.L.K.) and the National Institute on ...1 Title Page Article Type: Regular Manuscript Title : CREST in the nucleus accumbens core regulates cocaine conditioned place preference, cocaine-seeking behavior, andAug 30, 2013 · CaMKII and Protein Kinase A (PKA) are thought to be critical for synaptic plasticity and memory formation through their regulation of protein synthesis. Consistent with this, numerous studies have reported that CaMKII, PKA and protein synthesis are critical for long-term memory formation. Recently, … Janine L. Kwapis; Article 01 Jun 2023. Early life stress in male mice blunts responsiveness in a translationally-relevant reward task. Erin E. Hisey; Emma L. Fritsch; William A. Carlezon Jr.Janine L. Kwapis1, Sydney Trask 1, Shane E. Pullins1 & Fred J. Helmstetter1 Associations learned during Pavlovian fear conditioning are rapidly acquired and long lasting, providing an ideal model for studying long-term memory formation, storage, and retrieval. During retrieval, theseJanine L. Kwapis Present address: Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA, 16802, USA ...Finally, Bellfy and Kwapis review the evidence that the reconsolidation process may allow existing memories to update in response to new, relevant information . In their review, the authors outline the major behavioral paradigms used to study reconsolidation and describe the different molecular mechanisms across the brain that support this ...Author links open overlay panel Janine L. Kwapis 1, Timothy J. Jarome 2, Jonathan L. Lee, Fred J. Helmstetter. Show more. Add to Mendeley. Share. ... (Kwapis, Jarome, Lee, Gilmartin, & Helmstetter, 2014) and have hypothesized that trace memory may be stored in a distributed cortical network that includes prelimbic and retrosplenial cortices ...Janine L. Kwapis, Yasaman Alaghband, Alberto J. López, Jeffrey M. Long, Xiang Li, ... AG051807, and AG050787 to M.A.W., the National Institute on Aging Grants F32 AG052303 and K99 AG056596 to J.L.K., and in part by the Intramural Research Program of the National Institute on Aging. We thank Dr. Timothy Bredy for his help developing the HA ...While the anterior cingulate (ACC) and retrosplenial (RSC) cortices have been extensively studied for their role in spatial navigation, less is known about how they contribute to associative learning and later memory recall.White AO, Kramár EA, López AJ, Kwapis JL, Doan J, Saldana D, Davatolhagh MF , Alaghband Y , Blurton-Jones M, Matheos DP , Wood MA (2016) BDNF rescues BAF53b-dependent syn-Janine Kwapis, assistant professor of biology at Penn State, appointed as the Paul Berg Early Career Professor in the Biological Sciences About Eberly Leadership Meet the Dean Dean's Executive Team Sustainability Council Vision, Mission, and …Nicole C. Ferrara 1,2 Janine L. Kwapis 3 Sydney Trask 4,5* 1 Discipline of Physiology and Biophysics, Rosalind Franklin University, North Chicago, IL, ... Kwapis, J. L., Jarome, T. J., Schiff, J. C., and Helmstetter, F. J. (2011). Memory consolidation in both trace and delay fear conditioning is disrupted by intra-amygdala infusion of the protein …Neurobiology of learning and memory 128, 103-109. , 2016. 114. 2016. Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or amygdala, but not the medial prefrontal cortex. MR Gilmartin, JL Kwapis, FJ Helmstetter. Neurobiology of learning and memory 97 (4), 452-464. Timothy J. Jarome, Craig T. Werner, # Janine L. Kwapis, # and Fred J. Helmstetter * Efthimios M. C. Skoulakis, Editor. Author information Article ... Mouledous L, Frances B, et al. Protein degradation, as with protein synthesis, is required not only during long-term spatial memory consolidation but also reconsolidation. Eur J Neurosci. ...Jan 19, 2023 · The circadian clock plays a prominent role in neurons during development and throughout aging. This review covers topics pertinent to the role of 24-h rhythms in neuronal development and function, and their tendency to decline with aging. Pharmacological or behavioral modification that augment the function of our internal clock may be central to decline of cognitive disease and to future ... Bellfy L, Kwapis JL. Molecular Mechanisms of Reconsolidation-Dependent Memory Updating. International Journal of Molecular Sciences. 21. PMID 32916796 DOI: 10.3390/ijms21186580 : 0.88: 2020: Wright DS, Bodinayake KK, Kwapis JL. Investigating Memory Updating in Mice Using the Objects in Updated Locations Task. Current Protocols in Neuroscience ...Graham D. L. et al. Dynamic BDNF activity in nucleus accumbens with cocaine use increases self-administration and relapse. Nat. Neurosci. 10, 1029–1037 (2007). [Google Scholar] Graham D. L. et al. Tropomyosin-related kinase B in the mesolimbic dopamine system: region-specific effects on cocaine reward. Biol. Psychiatry 65, 696–701 (2009).Christopher W. Butler, Ashley A. Keiser, Janine L. Kwapis, Nicole C. Berchtold, Vanessa L. Wall, Marcelo A. Wood, Carl W. Cotman; Exercise opens a temporal window for enhanced cognitive improvement from subsequent physical activity; Learn Mem. 2019 Dec; 26(12): 485-492. ... Daniel L. Gillen, Pierre Baldi, David A. Bennett, Aron S. Buchman ...Expression of NURR2C in the vMHb alters reinstatement behaviors. HT22 cells either expressing V5-NURR2C alone (lane 1 and lane 2) or co-expressing V5-NURR2C and untagged NR4A2 (lane 3 and lane 4).Lauren Bellfy and Janine L. Kwapis * Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA 16802, USA; [email protected] - Kwapis, Janine L. N1 - Funding Information: This work was supported by the National Institutes of Health (grants R00AG056596 and R21AG068444) awarded to J.L.K.; the Whitehall Foundation (grant 2020-05-06 to J.L.K.); and was conducted while Janine Kwapis was a Glenn Foundation for Medical Research and AFAR Grant for Junior Faculty …Neurobiology of learning and memory 128, 103-109. , 2016. 114. 2016. Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or amygdala, but not the medial prefrontal cortex. MR Gilmartin, JL Kwapis, FJ Helmstetter. Neurobiology of learning and memory 97 (4), 452-464.Research Articles, Behavioral/Cognitive Janine L. Kwapis, Yasaman Alaghband, Alberto J. López, Jeffrey M. Long, Xiang Li, Guanhua Shu, Kasuni K. Bodinayake, Dina P. Matheos, Peter R. Rapp and Marcelo A. Open in Who Shared Wrong byline? This byline is for a different person with the same name. ...Following fear conditioning, behavior can be reduced by giving many CS-alone presentations in a process known as extinction or by presenting a few CS-alone presentations and interfering with subsequent memory reconsolidation.Protein Kinase Mzeta. PKMζ is an atypical isoform of protein kinase C (PKC) that is believed to actively maintain those cellular changes that occur during memory formation in order to preserve the memory engram over time. In vitro work has demonstrated that PKMζ is both necessary and sufficient to maintain established long-term potentiation ...Destiny S. Wright, 1 Kasuni K. Bodinayake, 1 and Janine L. Kwapis 1, * Destiny S. Wright 1 Department of Biology, Center for Molecular Investigation of Neurological Disorders (CMIND), Pennsylvania State University, University Park, PA, USA Europe PMC is an archive of life sciences journal literature.Timothy J. Jarome, Craig T. Werner., Janine L. Kwapis., Fred J. Helmstetter* Department of Psychology, University of Wisconsin, Milwaukee, Wisconsin, United States of America ... Citation: Jarome TJ, Werner CT, Kwapis JL, Helmstetter FJ (2011) Activity Dependent Protein Degradation Is Critical for the Formation and Stability of Fear Memory in ...Stainless-steel guide cannulas (26 gauge, 8-mm length) were implanted bilaterally 1 mm above either the dorsal hippocampus (A/P, −2 mm; M/L, ±1.3 mm; D/V, 1 mm) or the ventral hippocampus (A/P, −3.6 mm; M/L, ±3 mm; D/V, 3.3 mm; relative to dura and bregma; Franklin and Paxinos, 1997), then fixed in place with dental cement and two …Our results demonstrate that impairments in Nr4a2 expression accompany cognitive deficits in aged mice and rats. Further, HDAC3 contributes to this age-related …Activation of N-methyl-D-aspartate receptors (NMDAR) in the prelimbic medial prefrontal cortex (PL mPFC) is necessary for the acquisition of both trace and contextual fear memories, but it is not known how specific NR2 subunits support each association.Janine L. Kwapis, Department of Biology, The Pennsylvania State University, 208 Mueller Laboratory, University Park, PA 16802, USA; e-mail: [email protected]. Metrics and citations Metrics. Journals metrics. This article was published in Journal of Biological Rhythms. VIEW ALL JOURNAL METRICS.Janine L. Kwapis, Craig T. Werner ... the well-established requirement for protein synthesis in the amygdala (TJ Jarome, JL Karbowski (Kwapis), and FJ Helmstetter, pers. comm.). The second retrieval did not alter Zif268 protein expression, but the altered protein synthesis requirement was related to a dephosphorylation of synaptic GluR1(Ser845 ...Janine L. Kwapis, Timothy J. Jarome and Fred J. Helmstetter; Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA; Corresponding author: fjh{at}uwm.edu; Abstract. The extinction of delay fear conditioning relies on a neural circuit that has received much attention and is relatively well defined. ...Timothy J. Jarome, Craig T. Werner, Janine L. Kwapis, Fred J. Helmstetter. Research output: Contribution to journal › Article › peer-review. 141 Scopus citations. Overview; Fingerprint; Fingerprint Dive into the research topics of 'Activity dependent protein degradation is critical for the formation and stability of fear memory in the ...Janine L. Kwapis; The circadian system influences many different biological processes, including memory performance. While the suprachiasmatic nucleus (SCN) functions as the brain's central ...Janine L. Kwapis, Marcelo A. Wood. Biology; Research output: Contribution to journal › Review article › peer-review. 69 Citations (SciVal) Overview; Fingerprint; Abstract. Post-traumatic stress disorder (PTSD) and other anxiety disorders stemming from dysregulated fear memory are problematic and costly. Understanding the molecular ...Contributors: Janine L. Kwapis; Timothy J. Jarome; Marieke R. Gilmartin; Fred J. Helmstetter Show more detail. Source: Marieke Gilmartin via Crossref Metadata …Learning, memory, fear conditioning, trace conditioning, optogenetics, electrophysiology, single-uniJanine L. Kwapis; Alberto J. López; André O. White; Osasumwen V. Aimiuwu; Amni Al-Kachak; Kasuni K. Bodinayake; Nicole C. Oparaugo; Richard Dang; Mariam Astarabadi; Dina P. Matheos; Marcelo A. Wood; Neurobiology of Learning and Memory. Published on 01 Nov 2017. 0 views XX downloads; XX citations; Context and Auditory Fear are …Ashley C. Heimann , Janine L. Kwapis * Department of Biology, Pennsylvania State University, University Park, PA 16802, USA ARTICLE INFO Keywords: Circadian rhythm Context fear conditioning CRISPR Per1 Retrosplenial cortex Sex differences ABSTRACTJanine L. Kwapis, Timothy J. Jarome, Jonathan L. Lee, Fred J. Helmstetter Biology Research output: Contribution to journal › Article › peer-review 64 Scopus citations Overview Fingerprint Abstract The retrosplenial cortex (RSC) is known to play a role in the ...L-type VDCCs participate in behavioral-LTP and memory retention. Yuan-Yuan Han, Xiao-Dong Wang, Li Liu, Hong-Mei Guo, ... Chu-Hua Li. Pages 75-83 View PDF. Article preview. ... Yasaman Alaghband, Janine L. Kwapis, Alberto J. López, André O. White, ... Marcelo A. Wood. Pages 94-104 View PDF.27 Agu 2021 ... ... Janine L Kwapis 4. Affiliation. Department of Psychological Sciences, Purdue University, West Lafayette, IN, 47907, United States. Department ...Jun 1, 2023 · Additionally, the RSC has been demonstrated to play an important role in both the retrieval (Corcoran et al., 2011) and formation (Kwapis et al., 2015; Urban et al., 2021) of contextual fear memory. Both the anterior RSC (aRSC) and the posterior RSC (pRSC) have been implicated in spatial memory, although these subregions may each support ... Consistent with this, exposure to new information is necessary for the reconsolidation process to be initiated; when retrieval contains only familiar information, the original memory remains stable (Diaz-Mataix, Ruiz Martinez, Schafe, LeDoux, & Doyere, 2013; Jarome, Ferrara, Kwapis, & Helmstetter, 2015; Kwapis et al., 2019; Kwapis, Jarome, Ferrara, & …26 Okt 2022 ... Janine is now an Assistant Professor of Biology at Penn State University, where her lab investigates the epigenetic and molecular processes that ...Europe PMC is an archive of life sciences journal literature. Search life-sciences literature (41,238,717 articles, preprints and more) (41,238,717 articles, preprints and more)Chad W. Smies a, Janine L. Kwapis a, ∗ a Department of Biology, Pennsylvania State University, University Park, PA b Department ofNeurobiology and Behavior, University California, Irvine, CA a r t i c l e i n f o Article Aginghistory: both Received 17 October 2022 Revised 3 February 2023 Accepted 18 February 2023 Available online 23 February ...Timothy J Jarome 1 , Janine L Kwapis , Wendy L Ruenzel , Fred J Helmstetter Affiliation 1 Department of Psychology, University of Wisconsin-Milwaukee Milwaukee, WI, USA. PMID: 24009566 PMCID: PMC3757295 DOI: 10.3389/fnbeh.2013.00115 Abstract

Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. by Janine L Kwapis, Yasaman Alaghband, Enikö A Kramár, Alberto J López, Annie Vogel Ciernia, André O White, Guanhua Shu, Diane Rhee, Christina M Michael, Emilie Montellier, Yu Liu, Christophe N Magnan, Siwei Chen, Paolo Sassone …. Www statefarminsurance com

janine l. kwapis

Europe PMC is an archive of life sciences journal literature.After a spinal cord injury, axons fail to regenerate in the adult mammalian central nervous system, leading to permanent deficits in sensory and motor functions. Increasing neuronal activity after an injury using electrical stimulation or rehabilitation can enhance neuronal plasticity and result in …Dina P. Matheos's 38 research works with 1,708 citations and 6,046 reads, including: Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer's DiseaseHervera A, Zhou L, Palmisano I, et al. (2019) PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure. The Embo Journal Kwapis JL, Alaghband Y, López AJ, et al. ( 2019 ) HDAC3-mediated repression of the family contributes to age-related impairments in long-term memory.Jun 19, 2019 · Aging is accompanied by cognitive deficits, including impairments in long-term memory formation. Understanding the molecular mechanisms that support preserved cognitive function in aged animals is a critical step toward identifying novel therapeutic targets that could improve memory in aging individuals. One potential mechanism is the Nr4a family of genes, a group of CREB-dependent nuclear ... Janine Kwapis, assistant professor of biology at Penn State, appointed as the Paul Berg Early Career Professor in the Biological SciencesThe circadian clock plays a prominent role in neurons during development and throughout aging. This review covers topics pertinent to the role of 24-h rhythms in neuronal development and function, and their tendency to decline with aging. Pharmacological or behavioral modification that augment the function of our internal clock may be central to decline of cognitive disease and to future ...Assistant Professor of Biology Department of Biology jlk855 Janine Kwapis Biography Education B.A., Psychology, Alma College M.S., Behavioral Neuroscience, University of Wisconsin-Milwaukee Ph.D., Behavioral Neuroscience, University of Wisconsin-Milwaukee Postdoc Training University of California, Irvine Research Interests Europe PMC is an archive of life sciences journal literature.All animals were handled for several days prior to surgery. Rats that underwent surgery were implanted with bilateral cannulas aimed at the amygdala [anteroposterior [AP], −2.8; Lateral [L], +/− 5.0; Ventral [V], −7.2]. Coordinates were chosen based on a rat brain atlas . Before surgery, each rat was anesthetized with an intraperitoneal ...Janine L Kwapis Memory is not a stable record of experience, but instead is an ongoing process that allows existing memories to be modified with new information through a reconsolidation-dependent ...Janine L. Kwapis, Timothy J. Jarome, Janet C. Schiff, and Fred J. Helmstetter1 Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA Memory for delay fear conditioning requires the synthesis of new mRNA and protein in the basolateral amygdala. It isJanine Lynn Kwapis Doctorate Assistant Professor Primary The Pennsylvania State University (PSU) University Park, United States Post Doctoral Researcher University of …Janine Kwapis Assistant Professor, Biology h-index 1482 Citations 24 h-index 2009 2023 Research activity per year Overview Fingerprint Network Grants & Projects (4) Research …DOI: 10.1016/j.cell.2010.01.024 Corpus ID: 448458; Autophosphorylated CaMKIIα Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines @article{Bingol2010AutophosphorylatedCA, title={Autophosphorylated CaMKII$\alpha$ Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines}, author={Baris Bingol and Chi-Fong Wang and David Arnott and Dongmei Cheng and Junmin Peng and Morgan Sheng ...Janine L. Kwapis. Scilit Preprints.org Google Scholar 3,4,* 1. Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University ....

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